RNS Number : 5984B Valereum PLC 01 October 2025 This announcement contains information which, prior to its disclosure, was inside information as stipulated under Regulation 11 of the Market Abuse (Amendment) (EU Exit) Regulations 2019/310 (as amended). Upon the publication of this announcement via a Regulatory Information Service, this inside information is now considered to be in the public domain. ​ 01/10/25 Valereum Plc ("Valereum", "VLRM" or the "Company") Option Agreement to Cancel 2 Million Warrants Valereum Plc (AQSE: VLRM) is pleased to announce that it has entered into an option cancellation agreement with a service provider to cancel 2,000,000 warrants exercisable at £0.005 over ordinary shares of £0.001 each in the Company ("Option Agreement" or "Option") ("Warrants"). The Company has paid £10,000 to acquire the Option which may be exercised by the Company in its sole and absolute discretion at any time within five months of the date of the Option Agreement being 26 September 2025 ("Option Period"), under which the Company may either (i) cancel the Warrants by paying the cancellation fee of £90,000 to the service provider, or (ii) if not exercised in the Option Period the Warrants shall, with the Company's consent, be assigned by the service provider to a new warrant holder with the consent of the Company. Subject to the Option not having been exercised by the Company during the Option Period, the Warrants shall, with effect from the expiry of the Option Period, be automatically transferred, assigned and novated by the service provider to a new warrant holder who will be bound to the original terms of the Warrants. The purchase of the Option by the Company is considered by the Directors to be in the best interests of the shareholders. For more information, and the chance to have your questions directly answered by the management team, please head to our interactive investor hub via: Investor Hub. For further information, please contact: Valereum Plc Karl Moss Tel: +44 7938 767319 Investor Hub Fortified Securities Guy Wheatley Tel: +44 203 4117773 AQSE Corporate Adviser First Sentinel Corporate Finance Brian Stockbridge Tel: +44 20 3855 5551 The Directors of the Company accept responsibility for the contents of this announcement. For more information, please visit the Company's website at www.vlrm.com or to engage with the Valereum management team directly by asking questions, watching video summaries and seeing what other shareholders have to say. Navigate to our Interactive Investor hub here: Sign Up This information is provided by RNS, the news service of the London Stock Exchange. RNS is approved by the Financial Conduct Authority to act as a Primary Information Provider in the United Kingdom. Terms and conditions relating to the use and distribution of this information may apply. For further information, please contact rns@lseg.com or visit www.rns.com. RNS may use your IP address to confirm compliance with the terms and conditions, to analyse how you engage with the information contained in this communication, and to share such analysis on an anonymised basis with others as part of our commercial services. For further information about how RNS and the London Stock Exchange use the personal data you provide us, please see our Privacy Policy. END NEXMBBRTMTAMMPA